The Repository @ St. Cloud State

Open Access Knowledge and Scholarship

Date of Award

8-1983

Culminating Project Type

Thesis

Department

Biology

College

College of Science and Engineering

First Advisor

David Mork

Second Advisor

Alfred Grewe

Third Advisor

Vincent Johnson

Fourth Advisor

Edward Weiskopf

Keywords and Subject Headings

Prenatal exposure to pentobarbital on plasma testosterone levels

Abstract

Sodium pentobarbital or saline (control) was administered to pregnant rats at 17-21 days of gestation.

Male offspring at either 21 or 120 days were sacrificed by cervical dislocation and blood was collected. The serum was separated for testosterone determination by radioimmunoassay (RIA).

Data from RIA were statistically analyzed by student's t-test yielding a 99.99% confidence level. Therefore pentobarbital permanently decreases the plasma testosterone level by 0.5 ng/ml in pubertal and adult male rats.

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.